Urology carries one of the larger specialty change sets for 2027, and it arrives on two fronts at once.
The prostate biopsy family is being completely modernized. The new structure distinguishes transrectal from transperineal approach, separates regional sampling from targeted lesion sampling, and introduces reporting for fusion-guided and in-bore MRI or CT guided biopsy, with a new add-on code for additional targeted lesions.
Approach, guidance method, targeting and lesion count all become code-determining elements, which means procedure notes that were sufficient in 2026 may not support the correct code in 2027.
At the same time, urologic diagnostics expand substantially.
Prostate cancer risk assessment testing and genomic expression profiling, genitourinary circulating tumor DNA testing, AI-supported bladder cancer pathology analysis, renal disease genetic panels, inherited kidney disorder testing, and kidney transplant rejection and fibrosis assays all gain reporting attention.
Bladder cancer cryotherapy adds a treatment reporting option.
These two halves demand different coding disciplines.
Procedural reporting turns on the operative note; molecular reporting turns on test methodology, analyte, specimen and whether the correct pathway is a Category I code, a Proprietary Laboratory Analyses code or an unlisted procedure, with coverage frequently the harder question.
The 2027 changes require attention to both procedural and diagnostic reporting. For prostate biopsies, approach, guidance method, targeting and lesion count become important code-determining elements.
For molecular and genomic services, accurate reporting depends on the test methodology, analyte, specimen and the appropriate reporting pathway, while coverage remains an important consideration.
Join R. Sharma for this focused 30-minute session covering the 2027 urology procedural and diagnostic changes, prostate biopsy modernization, genomic and molecular testing, and reporting pathways.
CPT® is a registered trademark of the American Medical Association. This educational program is not affiliated with or endorsed by the AMA. Code assignment does not guarantee coverage or payment. Attendees should review applicable federal, state and payer-specific requirements.
R. Sharma, is a seasoned healthcare professional with over 20 years of clinical and operational experience. As a registered nurse and midwife, his deep clinical foundation spans hands-on patient care, health information management, revenue cycle management, and health technology systems. He has held various leadership roles across both outpatient and inpatient settings, and was responsible for managing large-scale operations for one of the top 10 hospital groups in the United States. He brings a unique, frontline-informed perspective to discussions on healthcare delivery, operational efficiency, and technology integration.
